FA2011lecture3

FA2011lecture3 - Raw data doesn’t consist of ratios, but...

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Unformatted text preview: Raw data doesn’t consist of ratios, but numbers of individuals in a population belonging to each phenotypic class. For example, round X wrinkled F 1 all round X F 2 : 5474 round, 1850 wrinkled (7324 total) If data ¡t 3:1 ratio EXACTLY, expect 5493 round (75%) and 1831 wrinkled (25%) Are actual numbers close enough to expected numbers justify conclusion that this phenotype is controlled by alternate (dominant and recessive) alleles of a single gene? Use chi squared test to determine Incredibly easy fve step program For conducting… Chi Squared Test ¡or Mendelian Ratios 1. State “null hypothesis”: Mendelian ratio is observed (expected iF phenotype is controlled by alternate alleles oF a single gene, or two genes, exhibiting simple dominant/ recessive relationship) 2. Calculate expected number oF progeny in each class predicted by Mendel’s laws, e.g. 3:1 or 9:3:3:1 ratio 3. Calculate 4. Translate chi squared value into a p value = probability that observed results would be obtained iF the hypothesis is true...
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This note was uploaded on 01/16/2012 for the course BICD 100 taught by Professor Nehring during the Fall '08 term at UCSD.

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FA2011lecture3 - Raw data doesn’t consist of ratios, but...

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