FA2011lecture20

FA2011lecture20 - Today what if there is migra&on(gene ow...

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f(aa) f(Aa) f(AA) If there is inbreeding, f(aa) > q 2 ; f(AA) > p 2 ; f(Aa) < 2pq but inbreeding by itself does not Today: what if there is migra&on (gene ﬂow) or the popula&on is small (gene&c driF)?

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GENE FLOW: movement of alleles into or out of a population as a result of migration f(A) in “recipient” population = p R f(A) in “donor” population (migrants) = p D f(A) in conglomerate population = p C m = proportion of individuals in conglomerate population that are from the donor population (migrants), so 1 - m = proportion from recipient population p C = mp D + (1 – m)p R Δ p = p C - p R = mp D + (1 – m)p R - p R = mp D + p R - mp R - p R = mp D – mp R = m(p D - p R ) Note: as you would expect, if p R = p D then Δp = 0

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Probability of fixation = 1/(2 N) Probability of elimination = 1-1/(2 N) New mutations will arise at a frequency proportional to population size (N)
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This note was uploaded on 01/16/2012 for the course BICD 100 taught by Professor Nehring during the Fall '08 term at UCSD.

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FA2011lecture20 - Today what if there is migra&on(gene ow...

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