Cytoskeleton%20and%20Extracellular%20Matrix - Cytoskeleton...

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Cytoskeleton and Extracellular Matrix I. Cytoskeleton a) network of fibers extending throughout the cytoplasm i. organelles do NOT float freely in cytoplasm ii. kind of like our skeleton and muscle iii. especially important to eukaryotic cells because they lack cell wall b) contribute to cell shape and motility i. provides anchorage for some organelles/enzyme molecules ii. cell location/movement iii. contributes to force and tension on cell important to cell movement and structure c) connects organelles i. can interact with motor proteins transport vesicles as a way of communication between organelles d) can disassemble and reassemble i. changes shape of the cell e) 3 types: microtubules, microfilaments, and intermediate filaments II. Microtubules a) all eukaryotes have them b) protein/subunit: tubulin i. globular protein ii. heterodimer: dimer = 2 subunit, alpha and beta tubulin iii. type of protein structure? quaternary c) form hollow tubes i. -/+ ends - end near nucleus ii. + end can gain/lose tubulin more easily
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This note was uploaded on 01/14/2012 for the course BILD 1 taught by Professor Boulanger during the Winter '08 term at UCSD.

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Cytoskeleton%20and%20Extracellular%20Matrix - Cytoskeleton...

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