handout%205%20cytoskeleton%20and%20energy%20with%20Ans -...

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TA: Paul Shao [email protected] Sec A08, Wedn 6-7pm HSS1305 OH: Mon 11-12pm PCE Handout 5: cytoskeleton, metabolism and Gibb’s free energy Cytoskeleton: 1. Functions of cytoskeleton: a. Maintain cell shape, rigidity, and flexibility b. Cell movement c. Provide “highways” that connect different organelles d. Three types of cytoskeleton: microtubules, microfilament, intermediate filament 2. Microtubules: a. Functions include: a.i. Chromosome movement a.ii. “highway” for organelles a.ii.1. Ie. Transport vesicles from ER to Goglgi apparatus and to target organelles a.iii. Cell movement a.iii.1. Ie. Sperm cell has flagella, which acts like a tail a.iii.2. Ie. Cilia: acts like oars b. Motor proteins: b.i. Dynein: bending movement inwards toward nucleus b.ii. Kinesin: bending movement outward away from nucleus 3. Microfilament: a. Built from globular protein: actin b. Twisted double chain of actin subunits c. Bear tension (pulling force) within the cell d. Found in microvilli, a projection that increases cell surface area
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This note was uploaded on 01/14/2012 for the course BILD 1 taught by Professor Boulanger during the Winter '08 term at UCSD.

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handout%205%20cytoskeleton%20and%20energy%20with%20Ans -...

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