Problemset5 - BILD1 Winter 2011 Problem Set#5 Mitosis...

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BILD1 Winter 2011 Problem Set #5: Mitosis, Meiosis, Mendelian genetics. Human genetics 1. MITOSIS PROBLEM (a) Draw a picture of a diploid cell that has a genome consisting of TWO chromosomes called Chr1 and Chr2. (hint: since it is DIPLOID it will have two copies of Chr1 and two copies of Chr2) (b) Draw a picture of your cell with its chromosomes through the 4 stages of mitosis: prophase, metaphase, anaphase, telophase. At the end you should have two diploid cells. (c) Are these two cells you have created genetically identical? (d) Go back to your drawing in part B and on the metaphase diagram, label the metaphase plate, the centromeres, the centrosomes, the telomeres, the spindle. (e) Which cytoskeleton proteins are involved insetting up the spindle? Where is the kinetochore and which cytoskeletal component associates with the kinetochore? (f) What would happen during mitosis if the centromere was deleted from a chromosome? (g) What would happen during mitosis if one chromosome had TWO centromeres? 2. MEIOSIS PROBLEM . (a) Draw a picture of a diploid cell that has a genome consisting of TWO chromosomes called Chr1 and Chr2. (hint: since it is DIPLOID it will have two copies of Chr1 and two copies of Chr2) (b) Draw the 4 stages of Meiosis I. On the metaphase diagram, label the tetrads, the metaphase plate, the centromeres, the centrosomes, the, the spindle.
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