EAYH Lecture 6 Sept 15-1

EAYH Lecture 6 Sept 15-1 - 17/10/201110:51:00 Lecture6...

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17/10/2011 10:51:00 Lecture 6 9/15/11 The Environment and Chronic Disease Risk   John D. Groopman- focuses on liver cancer research in SE Asia This is last lecture worth of material that will be on next Thursday's exam!  2 years ago- more people died from CHRONIC disease than ACUTE disease.  Epidemiologic transition! Remarkable change in status of people on planet. Many of us have the good probability of living until 2100.  19 th  century was the “Chemistry Century” mauve – synthesized by Perkin, the founder of synthetic organic chemistry world. Synthesized it from coal tar. 1 st  synthetic die for mass production; spawned the  entire organic chemistry revolution. Spawned industry of many different products: azo-dyes (“butter yellow”) 1 st  antibiotics  also spawned huge health epidemic of workers – almost all of these chemicals  caused cancer in humans 20 th  century was the “Physics Century”
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physics excelled forward diagnostic technologies downside- medical uses of radiation cause health problems What is leading cause of breast cancer that we know of?  IONIZING RADIATION  in x-rays! (many women during the 1920s-40s were x-rayed for diagnosis of  tuberculosis- many of these women later developed breast cancer) 21 st  century is “Biology Century” driven by synthetic, mechanical and industrial process by using DNA to direct  self-assembly of materials DNA in oyster genome allows for expression of protein to pick up calcium  molecules. .. material-science directed biology manipulate genetic apparatus Demographics of health change: the last 100 years women's life expectancy has been increasing at the rate of 3 months/year since  1840? WHY? fewer women dying in childbirth! Women's life expectancy should reach 95 years round 2040-2050 Big dip in women's child expectancy in 1920- Spanish Flu. Spanish Flu originated  in Kansas!  Japan there has been a huge decline in life expectancy. Top 10 Causes of Death in U.S. in 1900:
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EAYH Lecture 6 Sept 15-1 - 17/10/201110:51:00 Lecture6...

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