chapter 12 review

chapter 12 review - Lecture 21 Chapter 12 DNA: The Carrier...

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Lecture 21 Chapter 12 – DNA: The Carrier of Genetic Information I. DNA (Deoxyribonucleic Acid) A. Nucleic acid that is the molecular basis of inheritance B. Mechanisms of DNA, repair are conserved in all organisms C. Genes that carry out the same function are evolutionarily conserved D. Contains genetic code 1. The nucleotide sequence of a DNA coding region determines the amino acid sequence of a protein a. Protein sequences can be represented as a series of 20 letters II. Evidence of DNA as the Hereditary Material A. Frederick Griffith’s Transformation Experiment, 1928 1. Injected mouse with live avirulent rough (R) cells; the mouse lived 2. Injected mouse with live virulent smooth (S) cells; the mouse died 3. Injected mouse with heatkilled S cells; the mouse lived S cells; the mouse died a. Living S cells were obtained from the last mouse b. Concluded that some substance from the dead S cells had been transferred to the living R cells and transformed them into S cells c. Transformation – permanent genetic change in which the properties of one strain of dead cells are conferred on a different strain of living cells B. Oswald Avery et al. Transformation Experiment, 1944 1. Treated R strain bacteria with highly purified DNA from S strain bacteria 2. These R strain bacteria were then transformed into S strain bacteria
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This note was uploaded on 01/18/2012 for the course BIO 101 taught by Professor Martin during the Fall '08 term at Rutgers.

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chapter 12 review - Lecture 21 Chapter 12 DNA: The Carrier...

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