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chapter 14 review

chapter 14 review - Lecture 23 Chapter 14 Gene Regulation I...

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Lecture 23 – Chapter 14: Gene Regulation I. Gene Regulation in Bacteria A. Transcriptionallevel Control 1. most common method for prokaryotes to regulate gene expression 2. organizes related genes into groups that are rapidly turned on & off as units a. allows synthesis of only gene products needed at particular time 3. requires rapid turnover of mRNA molecules to prevent messages from accumulating and continuing to be translated when not needed B. Constitutive Genes 1. encode proteins that are always needed & are always transcribed C. Operon 1. gene complex consisting of a group of structural genes with related functions, plus the closely linked DNA sequences responsible for controlling them 2. Structural Gene a. enzymecoding sequence of DNA 3. Promoter a. nucleotide sequence in DNA to which RNA polymerase attaches to begin transcription b. located upstream from coding sequences 4. Operator a. sequence of bases upstream from 1 st structural gene in operon b. controls mRNA synthesis 5. Repressor Protein a. binds tightly to operator to prevent transcription 6. Repressor Gene
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