Lecture 10

Lecture 10 - Lecture #10: vertebrate gut I) Stomach most...

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Lecture #10: vertebrate gut I) Stomach most vertebrates muscular pouch at end of esophagus Ruminants: several stomachs for processing and storage a. Mechanical breakdown a.i. Contraction of muscle layers b. Chemical breakdown -3 secretory cell types in stomach lining b.i. Parietal cells: Secrete H+ generate O-I N HCl in stomach Recal pH=-log [H+] b.ii. Acid conditions b.ii.1. Activation enzymes b.ii.2. Breakdown food b.ii.3. Kill microber b.iii. Chief Cells: Secrete pepsinogen (zymogen) an inactive precursor protein that gets activated (cleaved) at low pH in stomach to produce (endoproteins) pepsin, a specific endopeptiase b.iii.1. Pepsinogen 00>pepsin +fragments b.iii.2. Chief cells also secrete lipase b.iv. Mucus cells: b.iv.1. Secrete mucus to protect stomach lining from self-digestion b.iv.1.a. H+ enzymes, abrasion c. Stomach values c.i. Esophageal sphincter at stomach entrance retains acid in stomach c.ii. Pyloric valve: muscle sphincter at stomach exit:hold food till liquefied
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Lecture 10 - Lecture #10: vertebrate gut I) Stomach most...

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