EnzymeKinetics

EnzymeKinetics - 12/6/2011 Enzyme Kinetics Law Depends on...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
12/6/2011 1 Enzyme Kinetics Law Depends on Mechanism Remember our previous example If first mechanistic step is rate determining, rate law can be written from first step O 3 + 2 NO 2 O 2 + N 2 O 5 1. O 3 + NO 2 NO 3 + O 2 slow 2. NO 3 + NO 2 N 2 O 5 fast Rate = k[O 3 ][NO 2 ] More Complex Mechanism What if the second step is rate limiting? What if RDS is unknown? Using the Steady State Approximation , we can write a general rate law and determine which RDS fits the experimental evidence Your book presents steady state and other techniques, but steady state assumption works well for all situations generally encountered
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
12/6/2011 2 Breakdown of Ozone O 3 O 2 + O O + O 3 2O 2 Rate = k 2 [O][O 3 ] but O is an intermediate. How do we determine [O]? k 1 k 1 k 2 Steady State Approximation Assumption: concentration of intermediates stays about constant during reaction Low, constant [Intermediate] Rate of appearance = rate of disappearance
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/17/2012 for the course S 117 taught by Professor Stephenjacobson during the Fall '11 term at Indiana.

Page1 / 6

EnzymeKinetics - 12/6/2011 Enzyme Kinetics Law Depends on...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online