Glycogenworksheet - Glycogen Metabolism and Signal...

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Glycogen Metabolism and Signal Transduction From the Student Companion Self tes:t 1-5, 7-14, 16-25 Problems: 6, 9, 10, 13 General questions: Chemistry of glycogen synthesis and degradation 1) Describe the structure of glycogen. Use chemical structures as necessary. 2) What enzyme activities are required for glycogen breakdown? Describe what these enzymes do. 3) What enzyme activities are required for glycogen synthesis? Describe what these enzymes do. 4) What is meant by processivity? Give an example of a processive enzyme. 5) The synthesis of UDP-glucose requires UTP and glucose-1-phosphate. What would be the advantages and disadvantages of performing the same reaction using UDP. 6) Phosphorylase uses Pi as a substrate. What is the advantage of this? Cellular level regulation of glycogen phosphorylase 7) How many states of phosphorylase are there? Describe how they are interconverted and their level of activity. 8) What are the allosteric affectors of phosphorylase in muscle, and to what state
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