Unformatted text preview: What enzyme do these molecules inhibit? Show the transformation this enzyme catalyzes. 11) Show the steps involved in converting five carbon units into a C-10 unit and a C-15 unit used for steroid biosynthesis. 12) What is the name of the 30 carbon unit in steroid biosynthesis? Show the reaction used to activated the 30 carbon unit for subsequent cyclization. Draw the structure and name the product of cyclization of the 30 carbon unit. 13) Draw the structures and name each of the major molecules involved in the synthesis of estrone and testosterone. 14. What is the mechanism for aromatization of estrone? 15) What are the structures of the most active male and female sex hormones? 16) What are the two major strategies currently employed to combat receptor positive breast cancer? Name two molecules that exemplify this strategy. 17) What is the role of LDL in cholesterol metabolism? 18) List five means used to regulate cholesterol synthesis....
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- Fall '11