C485ExamII2010

C485ExamII2010 - C485 Exam II Fall `10 Name_ Legible...

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C485 Exam II Fall ‘10 Name___________________ Legible please! Do not use acronyms. Use structures whenever they are asked for, or appropriate. Your explanations should be brief . Overly lengthy answers with irrelevant or erroneous material will receive deductions. GOOD LUCK 1. (33 Pts total) Please answer the following questions about glycogen metabolism. Use chemical structures where indicated. a) 4 pts Draw the structure of the two different types of glycosidic linkages found in glycogen. b) 6 pts There are three chemical reactions required to degrade glycogen. Using structures and explanations show what these are. c) 5 pts Place the following steps of the reaction cascade of glycogen metabolism in the proper order: a) activation of protein kinase A b) formation of cyclic AMP by adenylate cyclase c) phosphorylation of phosphorylase b d) hormone binding to target cell receptors e) phosphorylation of glycogen synthase a and phosphorylase kinase first _____ ______ ______ _______ ______ last
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d) 8pts Using structures and explanations, describe the steps involved in the synthesis of glycogen via the Leloir pathway. e) 5 pts Place the following steps of the insulin signaling cascade in the proper order:
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C485ExamII2010 - C485 Exam II Fall `10 Name_ Legible...

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