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Unformatted text preview: C485 Exam IV Fall 10 Name___________________ Legible please! Do not use acronyms. Use structures whenever they are asked for, or appropriate. Your explanations should be brief . Overly lengthy answers with irrelevant or erroneous material will receive deductions. GOOD LUCK 1. (8 Pts) The compound shown below is an intermediate in the biosynthesis of cholesterol that is derived from acetate. Using the numbering system shown below for acetate, number this compound so it is obvious how it is derived from acetate. Please draw and number a six carbon intermediate in this pathway. OPP H 3 C O O- 1 2 2. (8pts) Describe the general mechanism used by cells to replace a carbonyl group with an amino group in nucleotide biosynthesis. Please use structures to illustrate your point. What are the nitrogen donors used in nucleotide biosynthesis? 3. (6 pts) What are the carbon donors for synthesis of the purine base in nucleotide biosynthesis? (name(s) or structure(s)) 4. (6 pts) What are the carbon donors for synthesis of the pyrimidine base in nucleotide biosynthesis? (Name(s) or structure(s))biosynthesis?...
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- Fall '11
- Ben Burlingham