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Section16 - MIT Department of Biology 7.014 Introductory Biology Spring 2005 Recitation Section 16 April 6-7 2005 Recombination and Pedigrees A

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7.014 Introductory Biology, Spring 2005 Recitation Section 16 April 6-7, 2005 Recombination and Pedigrees A. Chromosomes and Recombination 1. What is the physical basis of the genetic phenomenon of gene recombination? 2. Why is the recombination frequency between two genes correlated with the physical distance between the two genes? 3. Recombination can occur anywhere along the length of the chromosome. However, we have been relying on the fact that genes are inherited as discreet units. How do we reconcile these two things? (Hint: think about what usually is the difference between two alleles of the same gene.) 4. Why is the highest possible recombination frequency 50%? B. Pedigrees In 1901 a physician in London named Archibald Garrod had some new patients with an unusual condition: when their urine came into contact with air it turned black. 1. What is the wild-type phenotype? 2.
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This note was uploaded on 01/19/2012 for the course BIOL 7.014 taught by Professor Walker during the Spring '05 term at MIT.

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Section16 - MIT Department of Biology 7.014 Introductory Biology Spring 2005 Recitation Section 16 April 6-7 2005 Recombination and Pedigrees A

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