2009-10-14_-_Lecture_17

2009-10-14_-_Lecture_17 - Biochemistry 461 FS 2009 Michigan...

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Biochemistry 461 FS 2009 Michigan State University Bioenergetics: The Basics October 14, 2009 Lecture 17 Bioenergetics and Metabolism “...in general, respiration is nothing but a slow combustion of carbon and hydrogen, which is entirely similar to that which occurs in a lighted lamp or candle. ..the torch of life lights itself at the moment the infant breathes for the first time, and it does not extinguish itself except at death.” Metabolism is the sum of all chemical transformations taking place in a cell or organism. Anabolism is the building up of small molecules into larger and more complex molecules such as lipids, polysaccharides, proteins, and nucleic acid. This requires the input of energy. Catabolism is the degradative phase of metabolism. This phase releases energy. 2
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Bioenergetics and Metabolism 3 Nonlinear Metablic Pathways 4
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Key Metabolic Reactions 1. Oxidation-reduction reactions 2. Carbon-carbon bond formation/breakage 3. Internal rearrangements/isomerizations/eliminations 5 Key Metabolic Reactions 4. Group transfer reactions 5. Free radical reactions 6
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Laws of Thermodynamics First law: Principle of conservation of energy. For any physical or chemical change, the total amount of energy
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This note was uploaded on 01/17/2012 for the course NSC 461 taught by Professor Benning during the Fall '11 term at Michigan State University.

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2009-10-14_-_Lecture_17 - Biochemistry 461 FS 2009 Michigan...

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