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Unformatted text preview: TOXOPLASMOSIS A Risk In Pregnancy What is Toxoplasmosis? It is an infection caused by the parasite Toxoplasma gondii What causes Toxoplasmosis? The protozoan Toxoplasmosis gondii, is a coccidian, obligate, intracellular parasite responsible for zoonotic infections in man and other mammals Life Cycle: Two phases Intestinal and extraintestinal Toxoplasmosis gondii Oocysts- Only members of the cat family shed oocysts Toxoplasmosis gondii Trophozoites- Tachyzoites are the actively proliferating trophozoites, which are observed during the acute stage of infection Toxoplasmosis gondii Tissue cysts: Tissue cysts are found most commonly in the brain and in skeletal and cardiac muscle but can occur in any organ Signs and Symptoms: Fever Sore throat Sore muscles Tiredness Swollen glands Temporary blurred vision or loss of vision Diagnosis: Serological tests Polymerase chain reaction (PCR) Histological demonstration of the parasite and or its antigens (i.e. immunoperoxidase stain) Isolation of the organism Treatment: Treatment should be developed in consultation with an obstetrician and infectious disease specialist Combinations of anti-toxoplasmosis medications (plus leurovorin) Hospitalization may be necessary Prevention: Wear gloves when handling soil Wash hands with soap and water after outdoor activities When preparing raw meat, wash any cutting boards, sinks, knives and other utensils that touched the raw meat thoroughly with soap and hot water to avoid contaminating other foods Cook all meats thoroughly Prevention: Keep cats indoors and feed them dry or canned food rather than allowing them to have access to wild birds and rodents Prevention: Clean litter box everyday (because the parasite found in cat feces needs one or more days after it is past to become infectious) Thoroughly wash hands after cleaning litter box ...
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