Virology - MICROBIOLOGY LECTURES Viruses and Acellular...

Info iconThis preview shows pages 1–11. Sign up to view the full content.

View Full Document Right Arrow Icon
01/18/12 1 Viruses and Acellular Agents MICROBIOLOGY LECTURES Sofronio Agustin Professor
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
01/18/12 2 Lesson Objectives: At the end of the lesson, the students should be able to: Describe the structures and components of viruses, viroids and prions. Describe the mechanism of infection and replication of bacteriophages and animal viruses. Understand association between viruses and cancer and the phenomenon of viral latency and persistent infections.
Background image of page 2
01/18/12 3 Basic Terminology Viruses are obligate intracellular parasites and require living host cell genetic and metabolic machinery for reproduction. Viral genomes contain either DNA or RNA, not both. Nucleic acid enclosed in a protein coat called Capsid . Some are surrounded by membrane layer called Envelope, which may contain integral proteins such as Spikes. Tropism – property of viruses to infect specific host cells; determined by specific host receptors and viral glycoproteins.
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
01/18/12 4 Viruses and Bacteria Compared Bacteria Rickettsias/ Chlamydias Viruses Intracellular Parasite No Yes Yes Genome Both DNA & RNA Both DNA & RNA DNA or RNA Passage through bacteriologic filters No May pass through Yes Sensitive to Antibiotics Yes Yes No Sensitive to Interferon No No Yes
Background image of page 4
01/18/12 5 Virus Sizes and Shapes
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
01/18/12 6 Helical Viruses
Background image of page 6
01/18/12 7 Enveloped Helical Virus
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
01/18/12 8 Polyhedral Viruses An ICOSAHEDRON is a polygon with 12 triangular facets and 12 corners
Background image of page 8
01/18/12 9 Enveloped Icosahedral Virus
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
10 Complex Viruses Bacteriophages have icosahedral heads, sheathed tail and tail fibers for host cell attachment. Morphology akin to
Background image of page 10
Image of page 11
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 46

Virology - MICROBIOLOGY LECTURES Viruses and Acellular...

This preview shows document pages 1 - 11. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online