Glodowski lec 8

Glodowski lec 8 - LINKAGE and RECOMBINATION IN PROKARYOTES...

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LINKAGE and RECOMBINATION IN PROKARYOTES Bacteria, why is it an excellent model organism? It is cheap to maintain, easy and fast to propagate in large numbers, can study bacteria in pure cultures (all of the bacteria in the culture is going to have the same genotype = genetically homogenous). They are haploid (no dealing with dominance / recessiveness). You can directly apply the phenotype to the genotype. However, bacteria have a limited number of phenotypes to observe (sensitivity to bacteriophages, sensitivity to antibiotics, ability to grow on specific medium). We generally grow bacteria in liquid culture or petri dish. Bacteria that are wild type can be grown on minimal media (carbon source / sugar and ions). They are known as prototrophs. Bacteria that can’t grow on minimal media are mutants, known as auxotrophs (they have to be grown on complete media = adding back whatever they need).
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Glodowski lec 8 - LINKAGE and RECOMBINATION IN PROKARYOTES...

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