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Population_Genetics[1]

Population_Genetics[1] - Chapter 17 Population Genetics The...

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Chapter 17 Population Genetics
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The frequencies of the wild type (A) and mutant (a) alleles in 1000 people
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The frequencies of the 2 alleles in the homozygotes and the heterozygote
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Frequencies of the different gametes formed is determined by the genotypes of the parents
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The Hardy-Weinberg Principle Given the allele frequencies in the P 1 generation of A = p and a = q, the genotype frequencies in the F 1 generation are AA = p 2 , Aa = 2pq and aa = q 2
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A plot of p 2 , 2 pq and q 2 as a function of the allele frequencies ( p and q) The frequency of the heterozygote Aa (2pq) is highest at A (p) or a (q) = 0.33 to 0.67
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Punnett square showing the results of random mating with three alleles
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Application of the Hardy-Weinberg principle to the 3 alleles (I A , I B and I o ) responsible for the 4 human blood groups (AB, A, B, and O)
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Allele and genotype frequencies for a X-linked gene in males and females
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The frequencies of affected males and females for a recessive X-linked allele
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Effect of inbreeding on the genotype frequencies F = Inbreeding Coefficient.
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