3b_Anaerobic_Glycolysis_SV_V2 - Besides PCr,...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Besides PCr, macronutrients can be used in phosphoryla7on. ADP + Pi Glucose/Glycogen, FA, AA CO2, H20, Heat ATP Complete breakdown of Carbohydrate Glucose 2 Pyruvates 1 Anaerobic Glycolysis •  Anaerobic breakdown of •  Produces ________ amounts of ATP, but at a _______ rate. –  1 glucose molecule can be quickly metabolized to yield _____ ATP. Note. Carbohydrates are the ONLY macronutrient that are broken down anaerobically. Anaerobic Glycolysis: Similar to Fig. 2.5 Where does it occur? 2 Anaerobic glycolysis (con’t): What if muscle glycogen is the energy substrate instead of glucose? •  Muscle glycogen can also be broken down via anaerobic glycolysis. 3 Glycolysis Tutorials • Tutorial 1: • hLp://highered.mcgraw ­hill.com/sites/0072507470/student_view0/ chapter25/anima7on__how_glycolysis_works.html • Tutorial 2: • hLp://www.science.smith.edu/departments/Biology/Bio231/ glycolysis.html • Tutorial 3: • hLp://www.northland.cc.mn.us/biology/biology1111/anima7ons/ glycolysis.html Ques7ons? •  What is the net gain of ATP during anaerobic glycolysis: –  If glucose is the substrate? –  If muscle glycogen is the substrate? –  If liver glycogen is the substrate? 4 Recall: •  What is the importance of NAD (Nico7namide Adenine Dinucleo7de)? For An. G. to con7nue to func7on and produce ATP at a very high rate: 5 What is the purpose of lactate produc7on? •  The purpose of lactate produc7on is to: –  __________ so that anaerobic glycolysis may con7nue producing ATP at a high rate. Benefits of lactate produc7on •  Temp. storage of H+ •  “Buys 7me” 6 Problems with Lactate •  Because it is very acidic, its accumula7on will: Fate of lactate: in the Cell •  When O2 becomes available, 7 Fate of lactate: that has diffused into blood stream •  It goes to________ –  Converted to glucose then to glycogen (via the __________) Glycolysis: Overview 1.  Occurs in the __________. 2.  Anaerobic Glycolysis does not require oxygen to recycle __________. 3.  Without oxygen present, pyruvic acid produced by glycolysis becomes __________. 4.  1 mole of muscle glycogen produces (nets) _____ moles of ATP; 1 mole of glucose produces (nets) _____ moles of ATP because 1 mole is used to convert glucose to glucose ­6 ­phosphate 5.  Combined, ATP ­PCr and anaerobic glycolysis provide the energy for the first _____ min of all ­out ac7vity. 8 ATP ­PCr and Glycoly7c Systems Key Points   ATP ­PCr system –  Pi is separated from PCr by what enzyme? –  Pi is combined with _____ to form ATP –  Energy yield: 1 mole of ATP per _____ mole of PCr •  Glycoly7c system –  Glucose or glycogen is broken down to _____. –  Without oxygen, pyruvic acid is converted to _____. –  1 mole of glucose yields _____ moles of ATP (gross) –  1 mole of glycogen yields _____ moles of ATP (gross) Energy Sources for the Early Minutes of Intense Exercise: Review The combined ac7ons of the ATP ­PCr and glycoly7c systems allow muscles to generate force in the absence of oxygen; thus, these two energy systems are the major energy contributors during the early minutes of high ­ intensity exercise. 9 ...
View Full Document

Ask a homework question - tutors are online