MCDB Low Lecture #9

MCDB Low Lecture #9 - MCDB Low Lecture#9 Kinetochore The...

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MCDB Low Lecture #9 Kinetochore The location where the microtubules attach. Metaphase ( Chromosomes line up) Important Events Metaphase plate – the center of the spindle where the chromosomes are aligned. Building of the mitotic spindle is completed Metaphase checkpoint – this is a surveillance checkpoint, the cell is ensuring that the spindle is fully formed and is set to go Anaphase (pull apart) Important Events Cohesion proteins – holding the two chromatids of each chromosome together are destroyed In anaphase one of the chromatids of each duplicated chromosome moves to one pole, and the other chromatid moves to the opposite pole. In order for this to happen the cohesion proteins must be broken down Telophase ( cell separation) The cleavage furrow (animal cells) or cell plate (plant cells) form The spindle microtubules disassemble A nuclear envelope re-forms around the cluster of chromosomes at each pole The chromosomes de-condense to the interphase form.
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