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Histology 10-7 - Histology Cartilage No blood vessels or...

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Histology 10/7/11 Cartilage - No blood vessels or nerves in cartilage o Everything requires for things to diffuse through highly hydrated ECM - Can heal itself, but really slow - made up of chondrocytes and extensive amounts of extracellular matrix o proteoglycans and collagens o (don’t need to know all of the proteoglycans) o important to know that they are made from a lot of chondrin sulfates o fibronectin o matrix very insoluble o negative charge causes hydration, which prevents compression, allows for shock absorption - very little cartilage in adult human bodies o nose, ear sternum, articular cartilage/ articular surfaces - Perichondrium o layer of dense connective tissue outside of cartlage o present in all except in articular cartilage o has fibroblasts that will undergo mitosis, hyperplasia (which makes new cells) o hyperplasia has one daughter cell that begins maturation process o All chondrocytes exist within lacunum - Hyperplastic growth o Growth isn’t towards the lacuna, the mature cells are pushing the perichondrium farther out.
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