Histology 10-11

Histology 10-11 - Histology 10/11/11 Endochondral growth -...

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Histology 10/11/11 Endochondral growth - Hyaline cartilage in epiphysial plate responsible for growth, starts off as cap, ossification happens in te middle and at the end, forms plate, and eventually “closes” - In long bones, growth at end is caused by intramembranous ossification, in middle/growth caused by endochondral - Bony matrix in middle of shaft removed by osteoclasts so that it is hollow - Uncalcified matrix at tend is called reserve cartilage Steps of growth - Hyperplasia (zone of proliferation) - Hypertrophy - Calcification - Cartliage removal and bone deposition - Zone of bone resorption Growth - done as zone of hypertrophy pushes upwards because calcification and bone layers not compressible as it matures\ - rate at which it done is constant between upwards and resorbption, as size stays constant… until reserve cartilage becomes bone. Bones are a source of calcium - calcium in bony matrix can be precipitated to regulate blood calcium lvels - main thing that deposits it is calcitonin o is a thyroid hormone that stimulates osteocytes to deposit more calcium phosphate o NOT THE SAME AS WHEN OSTEOCLASTS GET RID OF BONE TO RESHAPE IT (they do it to remodel, not to regulate)
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This note was uploaded on 01/21/2012 for the course BIO 413 taught by Professor Dr.donaldlovett during the Fall '11 term at TCNJ.

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Histology 10-11 - Histology 10/11/11 Endochondral growth -...

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