Histology 11-21

Histology 11-21 - Histology 11/22/11 Skin - Largest organ...

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Skin - Largest organ in body - Looking mostly at epidermis - Has specific layers From basal lamina up… - Stratum basale (or stratum germinativum) o Undergoes mitosis o Cells are called keratinocytes o Extensive free ribosomes making keratin , which will form intermediate filaments (tonofilaments ) o Vitamin D production (?) - Stratum spinosum o Many cells o Characterized by keratin, lamellar bodies (these are cellular processes which have desmosomes and create interstitial tissue spaces), and desmosomes o Lamellar bodies contain glycolipids that will eventually be released out via exocytosis, which will coat the cell, prevents water loss o Start to see formation of keratohyaline granules , bind to tonofilaments. - Stratum granulosum o Becomes very basophilic. o Keratinization occurs here - Stratum lucidum o nuclei and organelles break dwn o apoptosis occurs o only in thick skin , which do not have hair follicles. o
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This note was uploaded on 01/21/2012 for the course BIO 413 taught by Professor Dr.donaldlovett during the Fall '11 term at TCNJ.

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Histology 11-21 - Histology 11/22/11 Skin - Largest organ...

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