CaseStudy_GeneRegulation

CaseStudy_GeneRegulation - Computational Science and...

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Computational Science and Engineering Computational Cell Biology Lecture 4 Case Study: Basic Modeling in Gene Expression Yang Cao Department of Computer Science
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Computational Science and Engineering DNA Structure and Base Pair
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Computational Science and Engineering Gene Expression Gene is just a small part of DNA. The gene expression follows the process of: DNA RNA Protein Gene expression shows big difference between prokaryotic and eukaryotic cells. Most of the models of gene networks proposed in literature are for prokaryotic cells.
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Computational Science and Engineering Transcription Transcription from DNA to RNA is based on the base pair. However RNA doesn’t have “T”, instead it has “U”, which pairs with “A” just as “T” does. DNA RNA
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Computational Science and Engineering The Process of Transcription 1. Binding 2. Initiation 3. Elongation 4. Termination Initiation figure
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Computational Science and Engineering Transcription (Continue) Transcription is carried out by the enzyme RNA Polymerase (RNAP) Several types of RNA are produced mRNAs rRNAs tRNAs Small RNAs (can regulate transcription) Transcription occurs only on one strand of DNA
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RNA Processing In Prokaryotic cells, mRNA can be immediately translated by ribosomes. In Eukaryotic cells, RNA has to be processed and then
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This note was uploaded on 01/23/2012 for the course CS 3824 taught by Professor Staff during the Fall '08 term at Virginia Tech.

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CaseStudy_GeneRegulation - Computational Science and...

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