gene-function-prediction

gene-function-prediction - Introduction GO FLNs GAIN...

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Introduction GO FLNs GAIN Results Other Algorithms Gene Function Prediction T. M. Murali Department of Computer Science Virginia Tech murali@cs.vt.edu http://bioinformatics.cs.vt.edu/˜murali CS 3824 October 4, 6, 11, 2011 T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms Data, Data, Data I 150 genomes sequenced, 100 microbial and 50 eukaryotic. I Computational identification of genes. I Systematic gene knockouts. I Gene expression data, proteomic data, metabolic data. I Molecular interaction networks, metabolic pathways. T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms to the System Keith Haring, Untited , 1986 Urs Wehrli, Tidying Up Art , 2003 I Molecular biology: what are the parts of the cell? what functions does each part perform? T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms to the System Keith Haring, Untited , 1986 Urs Wehrli, Tidying Up Art , 2003 I Molecular biology: what are the parts of the cell? what functions does each part perform? I Systems biology: how do the parts make up the whole? how do genes and their products collectively carry out complex cellular functions? I We need to understand how genes, proteins, and other molecules interact with other in different cell states, different tissues, and under different external conditions. T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms Sea Urchin (Strongylocentrotus purpuratus) I Very important in developmental biology. I Many principles of embryo development were discovered in the sea urchin. T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms A Cell T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms A Cell is a Modular T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms A Cell is a Modular T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms A Cell is a Modular Network T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms A Cell is a Modular Network T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms A Cell is a Modular Network that Computes T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms Network is Complex T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms Network is Complex T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms Network is Complex but Very Poorly Understood T. M. Murali CS 3824 Gene Function Prediction
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Introduction GO FLNs GAIN Results Other Algorithms Roadblock: What Functions Do Genes Perform?
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gene-function-prediction - Introduction GO FLNs GAIN...

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