Lecture 5 - 5:13 - Biology 172 Lecture 5: Friday, May 14,...

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1 Lecture 5: Friday, May 14, 2010 Biology 172 Today’s Outline Announcements • Exam 1 is Wed, May 18, In      class 1-3pm (200 pts) • My Office hours next week Tuesday :  Review in Tuesday’s  Discussion Properties of Eukaryotes - Information Processing - Synthesis - Export - Recycling - Matter Processing - Energy Processing - Cell Support
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2 Eukaryotic Cells Relatively large size makes it difficult for molecules to diffuse across the entire cell. Partially solved by breaking up the large cell volume into several smaller membrane-bound organelles
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3 Fig. 7.6 A
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4 Fig. 7.6B
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5 Properties of Eukaryotes 1. Information processing - in nucleus Contain a large nucleus surrounded by a double- membrane nuclear envelope . Nucleolus Nucleoplasm Nuclear lamina
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6 Nucleus contains the linear chromosomes in the form of chromatin . The nuclear lamina anchors chromosomes and maintains the overall shape\ structure of the nucleus. Fig. 7.7
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7 Properties of Eukaryotes 2. Synthesis Rough ER Smooth ER Other proteins - on cytosolic ribosomes (and in energy- processing organelles)
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8 Proteins are made on Ribosomes Ribosomes free in cytoplasm Proteins destined for organelles, cytosol Ribosomes bound to ER ( rER ) Proteins of the endomembrane system Proteins to be exported/secreted Ribosomes in energy-processing organelles Some proteins in mitochondria, chloroplasts
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9 Eukaryotic ribosomes are also made of RNA and protein and have a large and a small subunit. Many ribosomes are found in the cytosol , the fluid part of the cytoplasm . Fig. 7.8
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Endoplasmic Reticulum - organelle made of complex out- foldings of the outer nuclear membrane - Rough ER - has ribosomes attached - modifies proteins and directs their transport - Smooth ER - lacks attached ribosomes - involved in lipid & carbohydrate synthesis, steroid hormone production, detoxification Smooth ER Rough ER ER lumen Ribosomes Transport vesicle Smooth ER Rough ER 200 µm Nuclear envelope
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11 Rough Endoplasmic Reticulum ( rough ER ) a network of membrane-bound tubes and sacs that is continuous with the outer nuclear membrane. studded with ribosomes for protein synthesis Modifies proteins and directs their transport Fig. 7.9
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Smooth Endoplasmic Reticulum (smooth ER) lacks ribosomes and is responsible for lipid synthesis, steroid hormone production smooth ER also breaks down toxins. Fig. 7.11
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Lecture 5 - 5:13 - Biology 172 Lecture 5: Friday, May 14,...

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