16 - Total Body Irradiation

16 - Total Body Irradiation - Lecture # 16 (Ch. 18) Total...

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Total Body Irradiation (TBI) Tarun K. Podder, PhD, DABR Department of Radiation Oncology Brody School of Medicine Leo Jenkins Cancer Center East Carolina University March 15, 2011 Lecture # 16 (Ch. 18)
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Clinical Indications • To destroy the bone marrow and leukemic cells • To immunosuppress the patient prior to receiving a bone marrow transplant • Aplastic anemia, and a number of leukemias and lymphomas respond to this treatment
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TBI – patient positioning Schematic diagram illustrating patient setup geometry for the bilateral TBI technique.
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TBI – patient positioning Patient setup on the TBI couch for the bilateral technique.
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TBI – patient positioning Patient in the standing TBI position with the head turned sideways for shielding of the brain. A five half-value-layer Cerrobend block is mounted on an acrylic plate attached to the TBI stand. Commonly use AP-PA technique
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TBI – patient positioning Pediatric patient in the reclining TBI position on the floor. The legs are placed in the "frog-legged" position to cover the entire patient in the radiation field with adequate margins. Brain-sparing shielding block is placed on top of an acrylic tray to shadow the central part of the skull with the head turned sideways.
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TBI Dose Uniformity • What can be done to improve dose homogeneity? • Dose homogeneity is hard to achieve when the RT object changes with both shape and thickness Increasing treatment distance helps Increasing energy helps
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This note was uploaded on 01/21/2012 for the course PHYS 6720 taught by Professor Hu during the Spring '10 term at East Carolina University .

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16 - Total Body Irradiation - Lecture # 16 (Ch. 18) Total...

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