20 SRS S RT SBRT - Stereotactic Radiation Therapy Tarun K Podder PhD DABR Department of Radiation Oncology Brody School of Medicine Leo Jenkins

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Unformatted text preview: Stereotactic Radiation Therapy Tarun K. Podder, PhD, DABR Department of Radiation Oncology Brody School of Medicine Leo Jenkins Cancer Center East Carolina University March 31, 2011 Lecture # 20 (Ch. 21) What are SRS, SRT and SBRT? Stereotactic radiosurgery (SRS) of an intracranial lesion, or radiosurgery, combines the use of a stereotactic apparatus and energetic radiation beams to irradiate the lesion with a single treatment . Stereotactic Radiotherapy (SRT) utilizes the stereotactic apparatus and radiation beams for multiple fractions or treatments. Stereotactic Body Radiation Therapy (SBRT) is an extension of SRS and SRT to extracranial sites. Although SRS and SRT have been used for decades, SBRT is considered emerging and evolving technology. SRS, SRT, SBRT SRS, SRT, SBRT SRS, SRT, SBRT SRS SRS Fractionation - SRT • Stereotactic Radiotherapy made possible using re-locatable frames, masks • Gill –Thomas – Cosman (GTC), relocatable from Radionics/Tyco/Integra • GK recently developed relocatable • Bite block (dental impression); occipital pad • Accuracy in the region of about 2mm SBRT • Stereotactic Body Irradiation • SRS expanded to the rest of the body • Presents other challenges – moving body parts, internal and external • Need to develop more sophisticated tracking systems; more critical • Infrared markers, tracking systems, internal fiducials Surgery without a Knife!! 1. GammaKnife 2. X-Knife (X-ray Knife) 3. CyberKnife History of SRS • Lars Leksell coined the term Stereotactic Radiosurgery in 1951 • His aim – a method for ―the non-invasive destruction of intracranial…..lesions, inaccessible/unsuitable for open surgery • Leksell et al experimented with particle beams and linear accelerators • He and colleagues then designed the first Gamma Knife (GK) machine – 179 cobalt sources in a hemispheric arrangement • First unit operational in 1968 Stereotactic Radiosurgery • Highly focused Beam • One large Single Dose • Required immobilization; head frames • Accurate imaging techniques • Devices to ensure the accuracy of targeting – Fiducial Boxes • Target delineation aided by the new imaging modalities Stereotactic apparatus is an external device commonly used in surgery to guide biopsy needle to the target....
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This note was uploaded on 01/21/2012 for the course PHYS 6720 taught by Professor Hu during the Spring '10 term at East Carolina University .

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20 SRS S RT SBRT - Stereotactic Radiation Therapy Tarun K Podder PhD DABR Department of Radiation Oncology Brody School of Medicine Leo Jenkins

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