Lecture+25+Synthetic+materials

Lecture+25+Synthetic+materials - Biomaterial Scaffolds Ref...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Biomaterial Scaffolds Ref #1. Ch 15-16 1. Biomaterial properties 2. Synthetic materials: polymers 3. Tailor the materials 1.1. Surface properties • Cell-surface interactions 1. Biomaterial Properties Non-Specific: vander Waals forces, electrostatic forces, solvation forces, steric forces Specific: receptor-ligand binding • Protein adsorption: electrostatic forces and hydrophobic interactions rotein sistant surfaces: ioinert e g polyethylene glycol Protein-resistant surfaces: bioinert, e.g., polyethylene glycol (PEG), hydrophilic, high flexibility, steric repulsion • Topography • Surface characterization: x-ray photoelectron spectroscopy 1.2. Bulk properties Ionic bonding, covalent bonding, metallic bonding 1. Biomaterial Properties 1.3. Mechanical properties Matching with native tissues, elastic/viscoelastic 1.4. Thermal properties: e.g., thermo-sensitive hydrogels poly(N- isopropyl acrylamide) (PNIPAM) with phase transition temperature between 28-32ºC 1.5. Electrical properties: e.g., polyvinylidene fluoride (PVDF), piezoelectric property Example: PVDF
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
1.6. Biological properties
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/21/2012 for the course BIOE 116 taught by Professor Various during the Fall '10 term at University of California, Berkeley.

Page1 / 4

Lecture+25+Synthetic+materials - Biomaterial Scaffolds Ref...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online