MSE-BioE+118+2011+L_20+DD+_+Hydrogels

MSE-BioE+118+2011+L_20+DD+_+Hydrogels - MSE/BioE 118...

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MSE/BioE 118 Lecture #21 1. Hydrogels & Applications 2. Environmentally-Responsive Polymers Sol-Gel Transition Thermally-Responsive Hydrogels What Are Hydrogels? Insoluble hydrophilic polymer networks Chemical gels Covalently cross-linked during or after polymer synthesis Critical Mc, ‘infinite’ MW network, single macromolecule Physical gels Associative network / hydrogen, ionic, hydrophobic bonding Highly hydrated – mostly water High swelling ratio, can contain > 99% water, high Q Low volume fraction of polymer Water structure Very low interfacial energy in water Low contact angle with water Hydrogel Applications Industrial products Marine anti-fouling, anti-fog, lubricious coatings Consumer goods Diaper filling, moisture retention agents Food Gelatin, modified carbohydrates Biology Chromatography, cell culture Medicine Contact lenses, wound dressing, drug delivery, etc…
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Wound dressing Contact lenses Drug or biologic delivery Non-fouling or lubricious coatings Space-filling agents Sealants, adhesives, non-adhesives Tissue engineering scaffolds
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This note was uploaded on 01/21/2012 for the course C 118 taught by Professor Hayleylam during the Fall '11 term at Berkeley.

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MSE-BioE+118+2011+L_20+DD+_+Hydrogels - MSE/BioE 118...

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