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15 - OVARIANCANCER Di Wen M.D,Ph.D OVARIAN TUMOURS...

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OVARIAN CANCER Di Wen, M.D.,Ph.D
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2003-10-27 Ovarian Cancer 2    Definition                 Ovarian  tumors  may  arise  at  any  age,  but  are  commonest between  30 and 60.   1.Ovarian tumors are particularly liable to be or to become  malignant. 2.In their early stages they are asymptomatic and painless. 3.They  may  grow  to  a  large  size  and  tend  to  undergo  mechanical complications such as torsion and perforation. OVARIAN TUMOURS
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2003-10-27 Ovarian Cancer 3 Definition         In developed countries women have a lifetime risk of  developing ovarian cancer of about 1.4% which is  slightly greater than the risk of cervical or endometrial  cancers, but well below the 7% average risk of breast  cancer CARCINOMA OF THE OVARY
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2003-10-27 Ovarian Cancer 4 Risk Factor         Genetic factor  are sometimes involved as in the  Lynch Syndrome of familial breast colorectal and ovarian  cancer Ovulation induction  with Clomiphene over  more than year carries a l0-fold increased risk of ovarian  cancer,  Long-term ora1   contraceptive  use  reduces the incidence of ovarian cancers CARCINOMA OF THE OVARY
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2003-10-27 Ovarian Cancer 5 Incidence                 Nearly 25% of all ovarian neoplasm are  malignant Approximately 80 of them are  primary growths of the ovary the remainder  being secondary usually carcinomata CARCINOMA OF THE OVARY
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2003-10-27 Ovarian Cancer 6 Primary Carcinoma of the Ovary            80 of all cases of primary carcinoma of the  ovary arise in serous or mucinous cysts.  CARCINOMA OF THE OVARY
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2003-10-27 Ovarian Cancer 7 Solid Carcinoma of the Ovary                   This accounts for 10% of primary carcinoma. It is arise  commonly bilateral  but one tumor is usually larger than  the other. The ovarian shape is retained for a time and  there is a well-marked pedicle but soon the tumors become  fixed. Secondary deposits occur in the omentum and  ascites develops.           CARCINOMA OF THE OVARY
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2003-10-27 Ovarian Cancer 8 Symptoms due to Size               Lack of any specific symptoms, ovarian tumors are often large by the time the doctor is consulted. CLINICAL FEATURES OF OVARIAN TUMOURS
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2003-10-27 Ovarian Cancer 9         Menstrual function  is seldom  upset,  and  any  irregularity  is  attributed  to  the  patient’s  ‘time of life ’. 
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2003-10-27 Ovarian Cancer 10               She  may  have  noticed  that  her  clothes  are  getting  tight  ant attributed this to weight gain  or, if the abdominal swelling has coincided with  amenorrhea  she may believe herself  to be  pregnant.
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2003-10-27 Ovarian Cancer 11 Pressure Symptoms These are commonly increased frequency of micturition , gastro-intestinal
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