16 - Contrast Agents new

16 - Contrast Agents new - Contrast agents 38 1 substance,...

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38 1 Contrast agents
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38 2 substance, such as barium,iodine or air, used in radiography to increase the contrast of an image. A positive contrast medium absorbs x-rays more strongly than the tissue or structure being examined; a negative contrast medium, less strongly.
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38 3 Contrast is used in medical imaging to make normal structures and some lesions look more conspicuous. Contrast can be positive (e.g. the use of iodinated contrast in CT) or negative as in the use of air in double contrast barium studies. Contrast media is usually specific to the imaging modality and organ systems
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38 4 * X-ray contrast agents:- A) Intravascular contrast agents (iodinated) B) Barium .
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38 5 A) Intravascular contrast agents (iodinated) 1- High osmolar contrast They are organic acids consisting of: agents (HOCA) - Anion ( radiodense iodinated benzoic acid derivative) - Cation (Sodium or meglumine) - They are in clinical use since 1950s. - The osmolarity depends on the concentration (30-76 %) - Examples: - Diatrizoate ( Hypaque) - Iothalamate ( Conray )
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38 6 A) Intravascular contrast agents (iodinated) Low osmolar contrast agents (LOCA) – non-ionic Have a lower incidence of adverse reactions. Equally effective . Contains 300- 370 mg I/mL
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This note was uploaded on 01/21/2012 for the course PDBIO 305 taught by Professor Woods,a during the Fall '08 term at BYU.

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16 - Contrast Agents new - Contrast agents 38 1 substance,...

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