20 - Pregnancy-induced Hypertension syndrome(Hypertensive...

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Pregnancy-induced Hypertension syndrome (Hypertensive disorders complicating pregnancy) Professor of obstetrics and gynecology Lin Qi De
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Term : PIHs is an acute or specific hypertension of pregnancy which is peculiar to pregnant or puerperal women .Diagnosis of PIHs is made on the basis of development of hypertension with or without proteinuria ,edema ,or both after the twentieth week of gestation ,although the signs and symptoms may appear earlier with hydatidiform moles .
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Classification : 1. Mild : Bp ≥140/90mmHg or Bp has a rise of 30mmHg systolic pressure or 15 mmHg diastolic pressure (4/2 Kpa ) over the prepregnant level,with or without trace proteinuria or edema. (= 1. gestational hypertension) 2. Moderate :Bp <160/110 mmHg (<21.3/14.6 Kpa ) ,with proteinuria “+” or edema . (= 2. preeclampsia/mild) 3. Severe : Bp ≥160/110 mmHg (21.3/14.6Kpa), with proteinuria “++” or edema . (= 2. preeclampsia/severe) (1) preeclampsia : above-described signs with headache ,visual disturbances and tightness of chest.(= 2. preeclampsia/severe) (2) Eclampsia : the signs and symptoms of pre-eclampsia with convulsion . (= 3. eclampsia)
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Etiology : 1. Utero-placental ischaemia : Abnormal development of the placental bed vessels / shallow trophoblast invision in spiral arteries / acute arterosis / 2. Endothelial cell activation/dysfunction: Cytotoxic factors : oxygen free raicals /lipid peroxidation / very low density lipoprotein(VLDL) /fibronection / platelet derived growth factor(
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This note was uploaded on 01/21/2012 for the course PDBIO 305 taught by Professor Woods,a during the Fall '08 term at BYU.

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20 - Pregnancy-induced Hypertension syndrome(Hypertensive...

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