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Unformatted text preview: The Molecular Basis of Inheritance DNA Review • DNA – Polymer of nucleotides – Phosphodiester bonds Figure 16.5 • DNA – antiparallel sugar-phosphate backbones – nitrogenous bases • complementary base pairing – joined through hydrogen bonds Figure 16.7 Figure 16.8 DNA replication • parent molecule unwinds • two new daughter strands • made using base-pairing rules DNA replication Figure 16.9 DNA replication is semiconservative Getting Started: Origins of Replication • replication of a DNA molecule – origins of replication • two strands are separated A eukaryotic chromosome Figure 16.12 • Elongation of new DNA – replication fork – DNA polymerases • add nucleotides to the 3 ′ end of a growing strand Elongating a New DNA Strand Figure 16.13 Synthesis of leading and lagging strands Figure 16.14 Priming DNA Synthesis • DNA polymerases – can only add nucleotides to the 3 ′ end • The initial nucleotide strand – primer Figure 16.15 Other Proteins That Assist DNA Replication...
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This document was uploaded on 01/23/2012.
- Spring '09