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Unformatted text preview: AUTOIMMUNE DISEASES In spite of nature’s ways of preventing it, it is possible for one’s own immune system to lose the ability to distinguish self or to choose not to respond to self. The result is an attack on a tissue or tissues of the body. 1. Type I Autoimmunity--antibodies made in response to a virus find proteins on body cells that also react with the antibodies. Cells are destroyed. 2. Type II (Cytotoxic) autoimmune reactions involve production of antibodies which react to cell- surface antigens. Cells are not destroyed but other harmful effects occur. Myasthenia gravis and Grave’s disease are examples. 3. Type III ( Immune complex) autoimmune reactions involve the deposition of immune complexes (antigen-antibody complexes) which result in tissue damage. Examples are lupus and rheumatoid arthritis. 4. Type IV (Cell-mediated) autoimmune reactions involve attack by cytolytic T cells. Examples 4....
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This note was uploaded on 01/23/2012 for the course MCB MCB2010 taught by Professor Smith during the Fall '09 term at Broward College.
- Fall '09