{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

DNA REPLICATION - polymerase 5 DNA polymerase removes the...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
DNA REPLICATION DNA polymerase can add new nucleotides only to the 3' end, or in the 5'   3' direction.  Keeping this in mind, here are the steps in DNA replication: 1. Enzyme unwinds the double strand and proteins stabilize the unwound DNA. 2. A replication fork forms at a fixed site called the origin of replication. 3. One new strand, the leading strand, is synthesized continuously by DNA polymerase.  Available nucleotides from the cytoplasm are linked. 4. The other new strand, the lagging strand, is synthesized in little bits at a time. For each little  section, RNA polymerase synthesizes a short RNA primer, which is extended by DNA 
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: polymerase. 5. DNA polymerase removes the RNA primer and replaces it with DNA. 6. DNA ligase joins the bits of the lagging strand. In some bacteria, two replication forks form and move in opposite directions around the chromosome until they meet. DNA polymerase evaluates the new strand as it forms, checking that the new base is really complementary to the base of the parent strand. If an incorrect base sneaks in, the enzyme will snip it out and replace it. This is to ensure that very few mistakes are made in the copying process....
View Full Document

{[ snackBarMessage ]}

Ask a homework question - tutors are online