EFFECTIVENESS OF CHEMOTHERAPEUTIC AGENTS

EFFECTIVENESS OF CHEMOTHERAPEUTIC AGENTS - EFFECTIVENESS OF...

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EFFECTIVENESS OF CHEMOTHERAPEUTIC AGENTS  What do bacteria do that makes them resistant to an antibiotic?   1. Microbes release an enzyme that modifies or destroys the antibiotic. Penicillinase is an  example of this.   2. Something about the microbe changes and makes it difficult or impossible for the antibiotic to  penetrate into the bacteria. This often is a change in the outer membrane.   3. The microbe develops a way to pump out the antibiotic so fast it does little harm. Many  organisms can pump out tetracyclines, for example.    4. Microbe develops an alternate chemical reaction to the one the antibiotic blocks.   5. Microbe may make a slight change in whatever cell component the antibiotic attacks.
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This note was uploaded on 01/23/2012 for the course MCB MCB2010 taught by Professor Smith during the Fall '09 term at Broward College.

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EFFECTIVENESS OF CHEMOTHERAPEUTIC AGENTS - EFFECTIVENESS OF...

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