ENDOTOXIN1 - ENDOTOXINS .Thisisamembrane ,phospholipids,and...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
ENDOTOXINS   Endotoxins are a part of the outer membrane of gram-negative bacteria. This is a membrane  outside the peptidoglycan layer and consists of lipoproteins, phospholipids, and  lipopolysaccharides. The lipid portion of the lipopolysaccharide, called lipid A, is the endotoxin.  Endotoxins are lipopolysaccharides instead of proteins. They produce their effects after the gram- negative bacteria die and their cell walls undergo lysis. Some antibiotics used against gram- negative bacteria cause lysis of the cell wall and may temporarily make symptoms worse. All  endotoxins produce about the same signs and symptoms, although these may be more severe with  some organisms that with others. They include chills, fever, weakness, aching, and in extreme  cases shock and even death. They do this by stimulating macrophages to release excess amounts  of cytokines. Endotoxins can contribute to miscarriages. 
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/23/2012 for the course MCB MCB2010 taught by Professor Smith during the Fall '09 term at Broward College.

Page1 / 2

ENDOTOXIN1 - ENDOTOXINS .Thisisamembrane ,phospholipids,and...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online