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Unformatted text preview: HOW BACTERIAL PATHOGENS DAMAGE HOST CELLS Many microbes entering a host are destroyed by lysosomes. If the microbes manage to avoid this, they may cause damage in four main ways: 1. Using host's nuitrients 2. Causing direct damage in the immediate area of the invasion 3. By producing toxins that may be transported by blood and lymph to damage sites far from the original invasion 4. By causing the host to react with a hypersensitivity reaction USING HOST'S NUTRIENTS Some pathogens produce proteins called siderophores, which steal iron from transport proteins and make it available to the microbe. DIRECT DAMAGE Pathogens can enter host cells and multiply, killing the host cells and moving on to new host cells. Some bacteria can induce host cells to engulf them by a process resembling phagocytosis, but the bacteria are not then destroyed as usually occurs. In fact, they can move through the but the bacteria are not then destroyed as usually occurs....
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