MATURATION AND RELEASE

MATURATION AND RELEASE - MATURATIONANDRELEASE

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MATURATION AND RELEASE The assembly of the capsid usually occurs spontaneously when all components have been  synthesized. If the virus is an enveloped virus, the viral proteins to be included in the envelope  are synthesized in the host cell along with the rest of the viral proteins. These proteins are then  incorporated  into the plasma membrane of the host cell and added to the lipids and  carbohydrates already produced by the host cell for its own use. The new virions leave the cell by  budding, each pushing out a small section of the membrane and popping out of the cell,  completely wrapped in that bit of plasma membrane. The host cell can live for at least a while  during this process, and occasionally a host cell survives.    Nonenveloped viruses cause lysis of the host cell. The plasma membrane ruptures and new  virions leave through the opened area. This results in immediate death for the host cell. 
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This note was uploaded on 01/23/2012 for the course MCB MCB2010 taught by Professor Smith during the Fall '09 term at Broward College.

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MATURATION AND RELEASE - MATURATIONANDRELEASE

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