OTHER ANTIMICROBIALS

OTHER ANTIMICROBIALS - OTHER ANTIMICROBIALS MODEOFACTION...

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OTHER ANTIMICROBIALS     MODE OF ACTION COMMENTS ANTIFUNGAL DRUGS     P OLYENES         Amphotericin B Injury to plasma membrane Systemic fungal infections. Fungicidal. I MIDAZOLES TRIAZOLES Inhibition of plasma membrane synthesis.  Fungicidal.      Clotrimazole   Topical use for fungal infections of skin and   mucous membranes. Possibly fungicidal.      Ketoconazole   Topical use for fungal infections of skin; orally   for systemic fungal infections. Fungistatic.  Griseofulvin Inhibition of mitotic spindle. Rungal infections of skin. Fungistatic. Tolnaftate Unknown. Athlete’s foot. Fungicidal.  Flucytosine Inhibits DNA or RNA synthesis. Systemic fungal infections. Fungicidal. ANTIVIRAL DRUGS     Amantadine Blocks entry or uncoating.   Influenza A prevention .   N UCLEOSIDE   ANALOGS         Acyclovir, ribavirin,          ganciclovir, trifluoridine Inhibit DNA synthesis by reverse transcriptase Herpesvirus
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