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Unformatted text preview: PATHOGENIC PROPERTIES OF FUNGI, PROTOZOA, HELMINTHS, AND ALGAE 1. Fungi---some fungi can cause disease, but as a group they do not have a well-defined set of virulence factors. a. Some fungi do produce toxic chemicals. Trichothecenes are toxins that inhibit protein synthesis in eukaryotic cells. b. Two fungi that cause skin infections, Candida albicans and Trichophyton secrete proteases, which may modify host cell membranes to allow attachment of the fungi. c. The body may produce an allergic response to the fungus. d. At least one fungus organism, Cryptococcus neoformans , produces a capsule that helps it resist phagocytosis. One example of a fungus disease caused by a toxin is ergotism. This was common in Europe in the Middle Ages and is believed by some to have been the cause of the phenomena blamed on...
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- Fall '09