Unformatted text preview: success of chemotherapy is that some chemicals are more poisonous to microbes than to the host infected by the microbe First Synthetic Drug- First chemotherapy—used substances from nature such as plant products (folk medicine) Cinchona bark—quinine for malaria Willow bark—aspirin Foxglove—digitalis, congestive heart failure and diurectic against dropsy (excess fluid build-up in tissues) 1910, Paul Ehrlich found Salvarsan (arsenic derivative) effective against syphilis 1930’s sulfa drugs (sulfonamides) synethisized 1928, Alexander Fleming discovered penicillin by accident. Fungus infected his bacterial plates and inhibited the growth of his bacteria- Penicillin not extensively tested or mass produced until 1940’s...
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- Fall '09
- Microbiology, Edward Jenner, viral particles, vaccine good example