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Unformatted text preview: g. Collagenase 1). Breaks down collagen (fibrous connect. tissue) 2). Allows organism to invade tissue D. Viruses- virulent mechanisms 1. Obligate intracellular parasites 2. Effect on host cells a. Cytocidal effect - lysis of host cell b. Lysogeny - latent state 1) Recurrent infections 2) Transformation → neoplasms c. Inclusion bodies in host cells d. Multinucleated giant cells - infected cells fuse (up to 100 nuclei) e. Alter structure of host cells → autoimmune disease E. Fungi - virulent mechanisms 1. Tissue damage 2. Mycotoxins 3. Allergies – mold spores 4. Delayed hypersensitivity - tissue allergy (due to internal infections) F. Protozoans, Worms- virulent mechanisms 1. Tissue damage 2. Interfere with normal function 3. Waste products toxic to host 4. Delayed hypersensitivity - tissue allergy...
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