Chickenpox - Chickenpox Shingles Herpes varicella(zoster...

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Chickenpox, Shingles - Herpes varicella (zoster) Chickenpox (Varicella): Highly contagious, common in young children. Virulence: invades epithelium, m.m. Transmission: URT secretions - droplet nuclei; secretions from lesions - direct, indirect contact P/E: nasopharynx, conjunctiva Disease: Inc. pd. 2 - 3 wks. Virus multiplies in nasal passage bloodstream (viremia) skin, mucus membranes. Maculopapular rash - trunk face, neck extremities. Lesion begins as papule vesicle pustule ruptures, crusts (3-4 days) - see fig. pg. 488. Fresh lesions ("crops”) appear first 3 - 4 days. In adults can involve lungs, liver, spleen. Immunity: active infection life-long immunity Vaccine: viable virus Shingles (Zoster): Occurs in adults who have had chicken pox as children. Virus remains latent in sensory ganglia. When activated lytic cycle causes vesicular rash along path nerve. Can reoccur.
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This note was uploaded on 01/23/2012 for the course MCB MCB2010 taught by Professor Smith during the Fall '09 term at Broward College.

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