HOST DEFENSES - 1 HOST DEFENSES (RESISTANCE) 11. Complement...

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1 HOST DEFENSES (RESISTANCE) 11. Complement System a. Group of soluble proteins occurring primarily in plasma b. When activated proteins react in a specific series of overlapping reactions (complement cascade) c. Result of reactions: 1). Lysis cell membrane of microbe 2). Phagocytosis 3). Inflammation d. Activated in two ways 1) Non-specific resistance - activated by cell wall components + complement factors 2) Specific resistance - activated by antigen + antibody reaction + complement factors Nonspecific Resistance: Cell Wall + Complement Components Factors 1). Lysis of microbe’s Complement Cascade cell membrane C 2). Phagocytosis (series of over lapping reactions) 3). Inflammation Specific Resistance: Antigen + Antibody + Complement Factors D. Cellular Defenses - Phagocytes (Phagocytosis) 1. Phagocyte - engulfs and digests microbes/foreign particles. 2.
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HOST DEFENSES - 1 HOST DEFENSES (RESISTANCE) 11. Complement...

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