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Unformatted text preview: B. Factors that influence organisms ability to cause disease 1. Size of infecting dose - must be exposed to sufficient # organisms 2. Transmission a. Spread from host to host b. Depends on organisms ability to survive outside host 3. Portal of entry - organism must enter body in area in which it can grow, multiply (colonize) 4. Adherence to target tissue - pathogen must attach to host cells 5. Virulence of organism a. Measure of organisms ability to cause disease, severity of disease. b. Dependent on organisms invasiveness which is 1). Due to organisms physical and chemical characteristics 2). Enable organism to overcome body defenses, invade, produce injury...
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- Fall '09