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Unformatted text preview: Immunity: Temporary Vaccine: Toxoid - not very effective Bacillary dysentery (Shigellosis) - Shigella species Gram neg. bacillus - 4 species pathogenic for man. S. dysenteriae- most virulent. S. sonnei- least virulent, most common in U.S. S. dysenteriae- Virulence: Endotoxins, exotoxins Transmission: Fecal-oral route H 2 O, food Disease: Inc. pd. 1-4 d. Organism localizes in large intestine multiplies invades m.m. causing ulceration, bleeding intestinal lining (no perforation) severe inflammation fluid loss dysentery (stools mostly fluids with blood, pus, mucus), vomiting. Accom. by fever, severe abdominal pain, extreme weakness. Persists approx. 1 wk. - self-limiting. Complication: Can cause severe dehydration, electrolyte imbalance. Mortality rate high in infants, young children. No solid immunity. Vaccine: viable, oral - limited use...
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This note was uploaded on 01/23/2012 for the course MCB MCB2010 taught by Professor Smith during the Fall '09 term at Broward College.
- Fall '09