Peptic Ulcers of Stomach

Peptic Ulcers of Stomach - Immunity: Temporary Vaccine:...

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Peptic Ulcers of Stomach, Duodenum - Helicobacter pylori Gram neg. short spiral Virulence: Urea (product of protein metabolism) ammonia which neutralizes stomach acids. Disease: Migrates thru mucus coating of stomach lining attaches to cells reduces production of mucus inflammation. Complication: stomach cancer LOWER ALIMENTARY SYSTEM INFECTIONS Cholera - Vibrio cholera Gram neg., comma shaped Virulence: produces potent entero-exotoxin - causes cells m.m. of GI tract to lose large amts. fluids (up to 22 L/day) severe electrolyte imbalance. Transmission: Fecal-oral route - contaminated H 2 O, food Disease: localizes in small . Onset sudden - vomiting, abdominal pain, severe dysentery. Stools - cloudy fluids with mucus, organisms ("rice water stools") severe dehydration, electrolyte imbalance. High mortality rate (60%) - due to shock. Carrier state can occur after infection.
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Unformatted text preview: Immunity: Temporary Vaccine: Toxoid - not very effective Bacillary dysentery (Shigellosis) - Shigella species Gram neg. bacillus - 4 species pathogenic for man. S. dysenteriae- most virulent. S. sonnei- least virulent, most common in U.S. S. dysenteriae- Virulence: Endotoxins, exotoxins Transmission: Fecal-oral route H 2 O, food Disease: Inc. pd. 1-4 d. Organism localizes in large intestine multiplies invades m.m. causing ulceration, bleeding intestinal lining (no perforation) severe inflammation fluid loss dysentery (stools mostly fluids with blood, pus, mucus), vomiting. Accom. by fever, severe abdominal pain, extreme weakness. Persists approx. 1 wk. - self-limiting. Complication: Can cause severe dehydration, electrolyte imbalance. Mortality rate high in infants, young children. No solid immunity. Vaccine: viable, oral - limited use...
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This note was uploaded on 01/23/2012 for the course MCB MCB2010 taught by Professor Smith during the Fall '09 term at Broward College.

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